AHA 2017 The new guidelines now define hypertension as >130/80 mmHg, emphasize the need for lifestyle changes and specify details of accurate BP measurement methods.
AHA 2017 A post-hoc survey of the SPRINT examined whether the presence or absence of physician or nursing in the BP measurement changed the treatment effect.
Although midlife hypertension is more common in men, it was only associated with the risk of dementia in women, suggesting that hypertension is a modifiable risk factor for dementia in women.
In a SPRINT-eligible ACCORD-BP population, a high-risk cohort of diabetic patients, intensive BP control at a goal of <120 mmHg, reduced CVD outcomes.
Individuals previously considered “metabolically healthy obese” are still at higher CV risk compared with normal weight metabolically healthy persons, according to a large UK health record dataset.
ESC 2017 Posthoc SPRINT analysis shows that persons with SBP ≥160 mmHg and low Framingham risk score, have a higher risk of all-cause mortality with intensive treatment.
Multiple 24-hour urine collections are needed for reliable estimation of individual sodium intake and the associated CV and renal risk.
In a meta-analysis, dual quarter-dose combinations of BP-lowering agents were as effective as standard-dose monotherapy, whereas a quadruple quarter-dose combination was twice as efficacious.
In a population-based cohort, the cumulative burden of BP, serum total- and LDL-C, and smoking from childhood and adolescence, were independently associated with worse midlife cognitive performance.
Systematic review of RCT evidence suggests that some TCM medications might improve CV risk factors and some may exert beneficial effects on ASCVD and chronic HF. Not all studies are of high methodological quality.
A large meta-analysis demonstrated that treating patients to reduce SBP below currently recommended targets was associated with a significantly reduced risk of CVD and all-cause mortality.
Various stroke subtypes have different risk profiles particularly in younger individuals, supporting a more tailored primary and secondary stroke prevention strategy in younger patients.