Diabetes is now considered an important risk factor for cardiovascular disease, and a complex interplay of pathogenic factors complicates management of both diseases.
CV risk is high in obese women without metabolic abnormalities, as well as in women with hypertension, diabetes or hypercholesterolemia, independently of their body mass index.
EPCCS 2018 A recording of the lecture by Prof. Cos on the evidence fro diabetes and accelerated vascular disease, and which interventions can change this relationship.
Results from the PIONEER 2 trial in T2DM patients demonstrated a significant and superior improvement in HbA1c with semaglutide compared to empagliflozin.
ESC HF 2018 A large study on individual patient data shows that diabetic HF patients who are not obese have the highest mortality. Obesity attenuates the prognostic impact of beta-blockers.
Obesity in childhood that persists or worsens during adulthood is associated with higher risks of developing hypertension, T2DM, and dyslipidemia.
In his presentation, prof. Cos considered recent observations that novel classes of antidiabetic drugs can provide CV benefit in T2DM patients. Cos, Brotons and Hobbs discuss how this can improve management and outcomes of these patients.
Visit-to-visit variability in fasting measurements of HDL-c, TG, and LDL-c is predictive of coronary events, CV events, and TG and LDL-c variability is also predictive of incident diabetes.
EPCCS 2018 Slides prepared and presented by Dr. Xavier Cos (Barcelona, Spain), here offered as an educational service.
EPCCS 2018 An impression of the presentation of dr. Xavier Cos on diabetes and vascular disease, epidemiology and management options, given during the Annual EPCCS CV Summit.
In a data-driven cluster analysis of 6 variables in adult patients with newly diagnosed diabetes, 5 categories of patients were identified with different characteristics and risks of complications.
A genetic predisposition to higher childhood BMI was associated with an increased risk of type 2 diabetes, coronary artery disease, and cardio-metabolic traits in adult life.
Lifestyle importantly contributes to preventable morbidity and mortality. This EPCCS guidance document outlines the presented evidence on ingredients of successful behaviour change strategies and motivational interviewing, as well as which CV risk behaviours and clinical outcomes may be improved with various types of strategies.