Statin eligibility differs substantially in the 5 major guidelines, and this impacts on the potential prevention of ASCVD events, which is a function of the number of eligible persons for statin therapy.
Following a TV program on the French-German public network ARTE that denied the proven link between cholesterol levels and CVD, the potential effects of such disinformation are considered.
The randomised DIRECT trial evaluated a practical weight management program. On average, weigh reduced by 10 kg and almost half achieved and maintained remission of T2DM at 12 months after starting the intervention.
A summary of the main messages for primary care from the guidelines for Cardiovascular Prevention in clinical practice, released in 2016 by the Sixth Joint Task Force (ESC and other societies).
Patients with a history of MI have a higher risk of vascular dementia, particularly if they additionally have a history of stroke, probably due to common risk factors for both diseases.
In a large population-based study, high TG levels identified individuals at high CVD risk, who would not be definite eligible for statin treatment according to the 2016 ESC/EAS guidelines.
In the UK Biobank, a slow self-reported walking pace was associated with a higher risk of all-cause and CV mortality in women and men, particularly in those with a low BMI.
AHA 2017 A post-hoc survey of the SPRINT examined whether the presence or absence of physician or nursing in the BP measurement changed the treatment effect.
AHA 2017 A new analysis of CANTOS data shows that patients who achieved hsCRP <2 mg/L benefitted from a 25% reduction in MACE, irrespective of the dose of canakinumab.
Patients with SHTG treated with OM3-CA 2 g daily had a statistically significant reduction in TG and non-HDL-c concentrations compared with those treated with olive oil 2 g daily.
This review summarizes the rationale to specifically target IL-1beta to lower residual inflammatory risk, now shown to be effective in the CANTOS trial. Other potential targets are also discussed.
These data underscore the importance of prospectively monitoring lipid parameters in all patients starting psychotropic treatment, as these drugs may induce or exacerbate dyslipidemia.