European Primary Care Cardiovascular Society

Treat also older adults to lower LDL-c

5' education - Jan. 19, 2021 - Prof. Børge Nordestgaard, MD

Majority side effects of statins also present with placebo

3' education - Dec. 3, 2020 - Prof. Darrel Francis, MD

Widespread atherosclerosis in Swedish population

3' education - Dec. 3, 2020 - Prof. Göran Bergström, MD, PhD

Potentially no contradiction between omega-3 fatty acids trials

3' education - Dec. 3, 2020 - Prof. Deepak Bhatt, MD

The therapeutic options in HFrEF patients

3' education - Dec. 3, 2020 - Prof. Marc Pfeffer, MD, PhD

Omega-3 carboxylic acid has no effect on MACE in high risk patients

3' education - Dec. 3, 2020 - Prof. Michael Lincoff, MD

A polypill with or without aspirin to reduce global CVD burden

3' education - Dec. 3, 2020 - Prof. Salim Yusuf, MD

Reduced HF hospitalization in patients with iron deficiency after acute HF treated with ferric carboxymaltose

5' education - Dec. 3, 2020 - Prof. Piotr Ponikowski, MD, PhD

An update on COVID-19 at the AHA Scientific Sessions

10' education - Dec. 3, 2020 - Anthony Fauci, MD

2019 ESC guidelines on diabetes, pre-diabetes and CVD

10' education - Dec. 2, 2020 - Prof. Francesco Cosentino, MD

CVD prevention with GLP-1 receptor agonists

10' education - Nov. 10, 2020 - Prof. Kamlesh Khunti, MD

To achieve lower LDL-c goals, combination therapy is necessary

3' education - Oct. 28, 2020 - Prof. Kausik Ray, MD

Reducing CV risk in diabetes in primary care

10' education - Oct. 27, 2020 - Prof. Richard Hobbs, MD

Primary outcome reduced by anti-inflammatory drug in chronic coronary disease

3' education - Sep. 30, 2020 - Mark Nidorf, MD

Temporarily suspending or continuing ACEi/ARBs in hospitalized patients with COVID-19

3' education - Sep. 30, 2020 - Prof. Renato D. Lopes, MD, PhD

Consideration of BP lowering irrespective of prior CVD or baseline SBP

3' education - Sep. 30, 2020 - Kazem Rahimi, MD

Changes in the 2020 AF guidelines

3' education - Sep. 30, 2020 - Prof. Isabelle van Gelder, MD

All three end points show benefit with another SLGT2 inhibitor in HFrEF

3' education - Sep. 16, 2020 - Milton Packer, MD

SGLT2i provides nephroprotective effects in CKD patients

3' education - Sep. 16, 2020 - Prof. Hiddo Heerspink, PhD

Improved outcomes with early rhythm control in AF

3' education - Sep. 16, 2020 - Prof. Paulus Kirchhof, MD

Diabetes and insulin resistance are strongest risk factors for premature onset of CHD in women

Literature - Feb. 11, 2021 - Dugani SB et al., - JAMA Cardiol. 2021

This study investigated the relative risk of more than 50 clinical risk factors and biomarkers with incident CHD in 4 age groups in women.

Reduced CV outcomes with larger early LDL-c lowering after MI in real-world setting

Literature - Feb. 4, 2021 - Schubert J, et al. - Eur Heart J 2021

Large-scale observational data from the SWEDEHEART registry showed that in patients in clinical practice early and aggressive LDL-c lowering after MI was associated with reduced risk of major CV outcomes and mortality.

Alcohol consumption is associated with increased risk of incident AF

Literature - Jan. 28, 2021 - Csengeri D et al., - Eur Heart J. 2021

This study in a large community-based cohort showed that even low amounts of alcohol consumption are associated with increased risk of incident AF.

The global burden of CVD and risk factors: An overview from 1990 to 2019

Literature - Jan. 22, 2021 - Roth GA, et al. - J Am Coll Cardiol. 2020

Global CVD burden has increased in almost all regions outside high-income countries. The increase was largely due to population growth and aging. In addition, attribution of risk factors like SBP, BMI, and dietary risk increased worldwide.

High risk for poor outcomes in patients with HF hospitalized for COVID-19

Literature - Jan. 22, 2021 - Alvarez-Garcia J, et al. - J Am Coll Cardiol. 2020

Patients with HF admitted to hospital for COVID-19 had increased risk for in-hospital mortality and needed more often ICU care and intubation and mechanical ventilation compared to patients without HF.

Lower mortality with higher proportion vigorous physical activity

Literature - Jan. 21, 2021 - Wang Y, et al. - JAMA Intern Med 2020

A nationally representative cohort study of US adults showed that a higher proportion of vigorous physical activity to total physical activity (moderate to vigorous) was associated with lower all-cause mortality.

Dysfunction of the endothelium in COVID-19

Literature - Jan. 21, 2021 - Evans PC et al., - Cardiovasc Res. 2020

This position paper discusses the cause and consequences of endothelial injury and dysfunction in COVID-19.

Elevated LDL-c associated with high absolute risk of MI and ASCVD in people aged 70–100 years

Literature - Jan. 21, 2021 - Mortensen MB & Nordestgaard BG., - Lancet. 2020

In a contemporary primary prevention cohort, MI and ASCVD event rates increased with higher LDL-c and older age.

Treat also older adults to lower LDL-c

5' education - Jan. 19, 2021 - Prof. Børge Nordestgaard, MD
Although relative risk for MI per 1 mmol/L higher LDL-c is similar across age groups, absolute risk for MI and ASCVD per LDL categories is much higher in individuals 80-100 years compared to those <70 years.

Although relative risk for MI per 1 mmol/L higher LDL-c is similar across age groups, absolute risk for MI and ASCVD per LDL categories is much higher in individuals 80-100 years compared to those <70 years.

In high CV risk overweight or obese subjects, remnant-c and TG associated with MACE

Literature - Jan. 6, 2021 - Castañer O, et al. - J Am Coll Cardiol. 2020

Triglycerides and remnant-c, but not LDL-c and HDL-c, were associated with MACE in a primary prevention cohort of high CV risk subjects with high prevalence of diabetes and obesity.

Increased CVD risk in offspring of mothers with poor CV health

Literature - Jan. 6, 2021 - Muchira JM, et al. - Eur J Prev Cardiol. 2020

Offspring of mothers with an ideal CVH score lived longer CVD free lives than children from mothers with a poor CV health pattern. The incidence rate for CVD was significantly higher among sons than daughters.

In older patients hospitalized for HF, prevalence of polypharmacy is high

Literature - Dec. 10, 2020 - Unlu O, et al. - Circ Heart Fail 2020

Findings of a study using real-world data from REGARDS showed that prevalence of polypharmacy, defined as ≥10 medications, is high in older patients hospitalized for HF.