The UMC Utrecht's Center for Circulatory Health has developed algorithms with which the risk of CVD and the effect of medication to reduce this risk, can be predicted for every adult. Use of the risk calculators is free.
The administration of low-dose aspirin had no beneficial effect for older individuals, but led to higher rates of major bleeding and all-cause mortality, compared with placebo.
EASD 2018 Following a review of the latest evidence, the EASD and the ADA introduced new recommendations on managing hyperglycemia in T2DM, including specific drug classes for some patients and enhancing medication adherence.
EASD 2018 Increased fasting glucose, higher BMI and impaired insulin sensitivity were detectable up to 10 years before the diagnosis of diabetes as well as prediabetes.
EASD 2018 Weight gain between the age of 10 and adulthood is associated with T2DM risk. Overweight children at age 10 appear to be at lower risk for developing T2DM than children who are regular weight at age 10 and then later become overweight as adults.
EASD 2018 A study found various clinical and biochemical factors that are associated with a greater risk of fast disease progression in T2DM patients.
In a retrospective cohort study, statin treatment was significantly related to a reduction in the incidence of ASCVD and in all-cause mortality in elderly T2DM patients aged <85 years, which reduced after the age of 85 years and disappeared in nonagenarians.
Higher alcohol consumption in young adults was, independently of sex and race, associated with more adverse cardiac remodeling after 20 years of follow-up, as shown by a cohort study.
BP lowering with amlodipine and lipid lowering with atorvastatin still resulted in lower rates of stroke and CV death in hypertensive patients after more than a decade, as the results of a long-term follow-up of data from the ASCOT trial show.
In patients with a systolic BP between 120 and <140 mmHg, a diastolic BP between 70 and <80 mmHg was associated with a lower risk of adverse outcomes as compared to lower and higher DBP.
An observational study showed longer consultations with minimal shared-decision making behavior by GPs during daily practice in 2015 compared with 2007, with less shared-decision making behavior in older patients.
The new guidelines on management of CVD during pregnancy consider new evidence on diagnostic techniques, risk assessment and drug therapy that became available since the 2012 edition.